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The protein efficiency ratio (PER) was significantly higher in the AFMMDA as compared to the control and MMDA. These results also indicated that protein intake was significantly higher in the control and OMC diet (T2) compared to aflatoxin B1-fed tilapia. Nevertheless, growth parameters were not affected among the treatments. The results from this study showed that MMDA significantly ( p < 0.05) improved the survival of fish by 16% as compared to the control group. These fish were housed in 18 aquaria (100 L) at a density of 50 fish/aquarium. Six diets as treatments (T1 = Control (C) T2 = Control + OMC 2 g/kg (OMC) T3 = Control + MMDA 2 g/kg (MMDA) T4 = AFB1 0.5 mg/kg (AF) T5 = AFB1 0.5 mg/kg + 2 g/kg OMC (AFOMC) T6 = AFB1 0.5 mg/kg + MMDA 2 g/kg (AFMMDA)) with similar crude protein levels (35.75 ± 0.35%) were formulated and fed to Nile tilapia fry (1.97 ± 0.1 g) for a period of 84 days. To reduce the impact of mycotoxins on Nile tilapia fry, two commercially available products-Organically Modified Clinoptilolite (OMC) and multi-component mycotoxin detoxifying agent (MMDA)-were used in this study. Mycotoxins can create serious health problems in aquatic and terrestrial animals, and their presence in agricultural products may result in significant economic losses. Mycotoxins have become a serious issue in the animal feed industry and have also affected the aquaculture industry.











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